THE COMPOSITION OF SWI/SNF CHROMATIN REMODELING COMPLEX IS STABLE DURING GENE TRANSCRIPTION.
The makeup of the SWI/SNF gene-controlling complex remains stable during gene activity
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Abstract
The stability of the SWI/SNF protein complex composition during gene transcription was demonstrated.
- The SWI/SNF complex is involved in various stages of gene transcription regulation.
- Specific subunits of the SWI/SNF complex participate at different stages of transcription.
- Differences in recruitment of certain SWI/SNF subunits may indicate the formation of distinct complexes that do not include the Brahma ATPase.
- Previous findings on the independent functioning of non-enzymatic subunits had not been established.
- This research provides new insights into the functional properties of proteins involved in chromatin remodeling.
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