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Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders
Using mTOR and Cell Recycling Processes to Treat Brain Diseases That Cause Memory and Movement Problems
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Abstract
More than 30 million individuals worldwide are affected by neurodegenerative disorders.
- Neurodegenerative disorders include Alzheimer's, Parkinson's, Huntington's diseases, epilepsy, stroke, and trauma.
- The mTOR protein kinase is involved in crucial cellular processes such as programmed cell death and neuronal cell development.
- Control of mTOR signaling may influence neuronal stem cell development, precursor cell differentiation, and cell survival.
- The relationship between apoptosis and autophagy is complex and significant in the context of mTOR functions.
- Further understanding of mTOR pathways is essential for developing new treatments for neurodegenerative diseases.
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