The effects of telmisartan alone or with hydrochlorothiazide on morning and 24-h ambulatory BP control: results from a practice-based study (SURGE 2)

Nov 17, 2012Hypertension research : official journal of the Japanese Society of Hypertension

Telmisartan alone or with hydrochlorothiazide and their effects on morning and all-day blood pressure control

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Abstract

A total of 863 patients experienced significant reductions in blood pressure with telmisartan treatment over 8 weeks.

  • Telmisartan, alone or with hydrochlorothiazide, lowered mean morning ambulatory blood pressure by 8.2 mm Hg.
  • Clinic blood pressure decreased by 22.3 mm Hg across the patient population.
  • Morning ambulatory blood pressure control improved from 36.5% to 64.4% after treatment.
  • Daytime ambulatory blood pressure control rose from 40.8% to 67.6% following the intervention.
  • 53.0% of patients achieved a 24-hour ambulatory blood pressure of less than 125/80 mm Hg.
  • Only 0.8% of patients reported any adverse events during the study.

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