The effects of telmisartan alone or in combination with hydrochlorothiazide on morning home blood pressure control: The SURGE 2 practice-based study

Aug 21, 2013Blood pressure

Telmisartan alone or with hydrochlorothiazide and their effects on controlling morning home blood pressure

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Abstract

A total of 25,882 patients were evaluated for the effects of telmisartan alone or with hydrochlorothiazide on morning blood pressure control.

  • Treatment with telmisartan alone or in combination with hydrochlorothiazide led to a statistically significant reduction in mean home blood pressure at morning, lunchtime, and evening.
  • Morning home blood pressure control improved from 10.6-19.8% to 51.1-64.6% after treatment.
  • Lunchtime home blood pressure control increased from 20.6-26.0% to 57.7-70.5%.
  • Evening home blood pressure control rose from 21.3-31.4% to 59.0-68.8%.
  • The morning home blood pressure response included a range of 62.6-67.5% for systolic and 81.4-87.0% for diastolic blood pressure.
  • Adverse events occurred in 1.2% of patients, indicating a low rate of reported side effects.

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