The Mid-Term Effects of Transit Bipartition with Sleeve Gastrectomy on Glycemic Control, Weight Loss, and Nutritional Status in Patients with Type 2 Diabetes Mellitus: a Retrospective Analysis of a 3-Year Follow-up

Jul 1, 2021Obesity surgery

Mid-Term Effects of Combined Stomach and Intestine Surgery on Blood Sugar, Weight Loss, and Nutrition in People with Type 2 Diabetes Over 3 Years

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Abstract

At 36 months after surgery, 84.3% of patients achieved remission of type 2 diabetes mellitus (T2DM).

The mean body mass index (BMI) decreased from 44.70 to 29.75 kg/m².
Total weight loss (TWL) averaged 33.84%, while excess weight loss (EWL) was 77.19%.
Mean low-density lipoprotein (LDL) levels significantly decreased compared to baseline.
No significant changes were observed in mean high-density lipoprotein (HDL), albumin, vitamin B12, or folic acid levels.

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BACKGROUND: Metabolic surgery is an effective treatment method for glycemic control and weight loss in obese patients with type 2 diabetes mellitus (T2DM). This study aimed to present the mid-term metabolic effects and weight loss results of the patients with T2DM who underwent transit bipartition with sleeve gastrectomy (TB-SG).

METHODS: A total of 32 obese patients with T2DM who underwent TB-SG were included in the study. The T2DM remission status after surgery was evaluated. The postoperative glycemic variables, weight loss, lipid profile, and nutritional profile were also compared with the baseline values.

RESULTS: At 36 months after surgery, T2DM remission occurred in 27 patients (84.3%) and the mean BMI decreased from 44.70 ± 9.34 to 29.75 ± 2.19 kg/m. The percentage of total weight loss (TWL) and excess weight loss (EWL) was 33.84% and 77.19%, respectively. The mean LDL values significantly decreased compared to baseline; however, the mean HDL did not significantly differ. No significant difference was observed regarding the mean albumin, vitamin B12, and folic acid levels. 2

CONCLUSION: TB-SG procedure seems promising in terms of T2DM remission and weight loss with less malnutrition and vitamin deficiency in treating obese patients with T2DM.

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The Mid-Term Effects of Transit Bipartition with Sleeve Gastrectomy on Glycemic Control, Weight Loss, and Nutritional Status in Patients with Type 2 Diabetes Mellitus: a Retrospective Analysis of a 3-Year Follow-up

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