Journal of the American Heart Association

Tirzepatide and the risk of irregular heartbeat in adults with overweight or obesity: an updated analysis of clinical trials

Updated

Abstract

Tirzepatide is a dual agonist that has demonstrated efficacy in weight loss and cardiovascular improvement.

  • The specific impact of tirzepatide on the occurrence of atrial fibrillation in individuals with overweight or obesity is not well understood.
  • Tirzepatide targets glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors.
  • Previous studies have shown tirzepatide's effectiveness in facilitating weight loss.
  • Tirzepatide is associated with improved cardiovascular outcomes.

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