Total and Cause-Specific Mortality of U.S. Nurses Working Rotating Night Shifts

Women with ≥5 years of rotating night shift work experience increased mortality rates.

• All-cause mortality risk is elevated in women with 6-14 years (HR 1.11) and ≥15 years (HR 1.11) of rotating night shift work compared to those who never worked night shifts.
• Cardiovascular disease (CVD) mortality risk is also higher for women with 6-14 years (HR 1.19) and ≥15 years (HR 1.23) of rotating night shift work.
• No significant association was found between rotating night shift work and overall cancer mortality, except for lung cancer.
• Women with ≥15 years of rotating night shift work have a higher risk of lung cancer mortality (HR 1.25).

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