Night-Shift Work and Risk of Colorectal Cancer in the Nurses' Health Study

Jun 5, 2003Journal of the National Cancer Institute

Night-shift work and risk of colorectal cancer in nurses

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Abstract

Working rotating night shifts for 15 or more years may increase the risk of colorectal cancer in women.

  • 602 cases of colorectal cancer were documented among 78,586 women.
  • Participants were followed from 1988 through 1998.
  • Women working 1-14 years of rotating night shifts had a relative risk of 1.00 for colorectal cancer.
  • Those working 15 years or more on rotating night shifts had a relative risk of 1.35.
  • A statistically significant trend (P(trend) = .04) was observed in the risk associated with night shift duration.

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