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Transcriptional control of circadian metabolic rhythms in the liver
How gene activity regulates daily metabolic cycles in the liver
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Abstract
Restoring the rhythmicity of body physiology may have important implications for human health and medicine.
- Diurnal metabolic rhythms play a crucial role in maintaining metabolic balance in mammals.
- Disruption of the alignment between the body clock and metabolism is linked to various health issues.
- The integration of liver glucose metabolism and the body clock involves a network focused on PPARγ coactivator 1 (PGC-1).
- Circadian control affects the regulation of the autophagy gene program in the liver.
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