Full text is available at the source.
Abstract
Restoring the rhythmicity of body physiology may have important implications for human health and medicine.
- Diurnal metabolic rhythms play a crucial role in maintaining metabolic balance in mammals.
- Disruption of the alignment between the body clock and metabolism is linked to various health issues.
- The integration of liver glucose metabolism and the body clock involves a network focused on PPARγ coactivator 1 (PGC-1).
- Circadian control affects the regulation of the autophagy gene program in the liver.
Simplified