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Ultrastructural characteristics of circadian pacemaker neurones, immunoreactive to an antibody against a pigment-dispersing hormone in the fly's brain
Detailed structure of daily rhythm nerve cells marked by a pigment-dispersing hormone in the fly brain
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Abstract
PDH-ir varicosities in two fly species show accumulation of dense core vesicles (DCVs).
- PDH-ir varicosities are identified as potential releasing sites for the PDH-like peptide within the neuronal circadian system.
- Both Drosophila melanogaster and Musca domestica exhibit similar ultrastructural features in PDH-ir varicosities.
- Post-embedding immuno-electron microscopy confirms the presence of PDH-like peptide within the dense core vesicles.
- The lack of synaptic specializations at PDH-ir varicosities suggests a mechanism of non-synaptic paracrine release for the peptide.
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