Visceral fat area is associated with a high risk for early postoperative recurrence in Crohn's disease

Oct 14, 2014Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Higher belly fat linked to greater risk of Crohn's disease coming back soon after surgery

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Abstract

A high visceral fat area (VFA) value is associated with postoperative clinical recurrence in Crohn's disease, with a hazard ratio of 2.63.

  • Postoperative endoscopic recurrence at 6 months is linked to a high VFA (P = 0.019) and mesenteric fat index (MFI) values above the median (P = 0.008).
  • VFA values show a strong correlation with endoscopic recurrence (r = 0.895, P = 0.040) and endoscopic lesions (r = 0.617, P < 0.0001).
  • MFI values are also correlated with endoscopic recurrence (r = 0.918, P = 0.02) and endoscopic scores (r = 0.584, P < 0.0001).
  • Multivariate analysis suggests that VFA values above the median could predict clinical recurrence in Crohn's disease.

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