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Voluntary exercise contributed to an amelioration of abnormal feeding behavior, locomotor activity and ghrelin production concomitantly with a weight reduction in high fat diet-induced obese rats
Voluntary exercise may improve eating habits, movement, and hunger hormone levels while reducing weight in rats made obese by a high-fat diet
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Abstract
Marked increases in body weight and visceral fat were observed in the high fat diet sedentary group.
- Voluntary exercise in high fat diet rats led to significant weight and fat reduction.
- Disrupted rhythms of feeding and locomotor activity were observed in sedentary high fat diet rats.
- Infrequent voluntary exercise restored abnormal rhythms of activity and eating in obese rats.
- Ghrelin production was negatively affected in high fat diet rats but improved with voluntary exercise.
- The findings suggest a link between ghrelin and the circadian rhythm of daily activity and eating behavior.
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