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A wearable biosensing platform for continuous monitoring of inflammatory and metabolic biomarkers for real‐time health tracking and personalized care
A wearable device for continuous tracking of inflammation and metabolism markers to support real-time health monitoring and personalized care
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Abstract
Significant classification performance was achieved for cortisol, melatonin, interleukin-6, and tumor necrosis factor-alpha with an Area Under the Curve >0.80.
- A dual-framework approach was developed for tracking hormone and immune responses through perspired sweat.
- Distinct circadian patterns of biomarkers were identified, varying by age, gender, and stress levels.
- Young adults showed clear separation in melatonin and cortisol phases, along with rhythmic immune responses.
- Older individuals displayed reduced biomarker amplitudes and shifted phases, indicating potential inflammatory dominance.
- Stress exposure led to earlier cortisol peaks, suppressed melatonin rhythms, and increased immune response variability, suggesting circadian misalignment.
- Sweat was validated as a reliable medium for real-time monitoring of endocrine and immune cycles.
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