Weight, body makeup, metabolism, and vitamin D changes in people with severe obesity treated with liraglutide 3 mg

Subjects with grade 3 and 4 obesity experienced a mean weight loss of 14.99 kg after 8 months of treatment with liraglutide 3 mg.

• Significant reductions in weight, BMI, and abdominal circumference were observed (p < 0.001).
• Participants lost an average of 13.04% of their initial weight after 8 months.
• Improvements in body composition included a significant decrease in fat percentage and fat mass (kg) (p < 0.001).
• The healthy visceral fat index increased to 67.17% (p < 0.001) at the end of the treatment.
• Blood pressure showed a significant reduction (p < 0.001), along with improvements in biochemical variables.
• A significant increase in 25-OH vitamin D levels was noted at the conclusion of the intervention (p < 0.001).

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