Weight loss and body composition after compounded semaglutide treatment in a real world setting

Jan 8, 2025Diabetes, obesity & metabolism

Weight loss and body fat changes after combined semaglutide treatment in everyday use

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Abstract

After 3 months, participants experienced an average weight loss of 4.11 kg (4.57%) while using compounded semaglutide/cyanocobalamin injections.

  • Fat mass decreased by an average of 2.67 kg, indicating a reduction in overall body fat.
  • Trunk fat mass specifically decreased by 1.10 kg, suggesting targeted fat loss in the abdominal area.
  • Participants lost small amounts of lean mass (1.43 kg) and skeletal muscle mass (0.88 kg), which may indicate muscle preservation.
  • The proportion of fat mass relative to total weight decreased, while lean muscle and skeletal muscle mass increased.

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