Acute dietary carbohydrate manipulation and the subsequent inflammatory and hepcidin responses to exercise

Sep 4, 2015European journal of applied physiology

How short-term changes in carbohydrate intake affect inflammation and iron regulation after exercise

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Abstract

Controlled low carbohydrate intake led to higher baseline hepcidin levels and post-exercise interleukin-6 responses than high carbohydrate intake.

  • Interleukin-6 levels were elevated immediately after exercise in both dietary conditions but were significantly lower following high carbohydrate intake.
  • Baseline hepcidin levels were higher after low carbohydrate intake compared to high carbohydrate intake.
  • A trend indicated lower hepcidin levels at 3 hours post-exercise with high carbohydrate intake, with a large effect size.
  • Post-exercise serum iron levels increased for both dietary conditions, while serum ferritin levels did not change.

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