Association between coffee, tobacco, and alcohol daily consumption and sleep/wake cycle: an actigraphy study in euthymic patients with bipolar disorders

A sample of 147 euthymic individuals with bipolar disorder showed significant associations between daily coffee, tobacco, and alcohol use and sleep/wake cycle parameters.

• Individuals with bipolar disorder reported higher rates of coffee, tobacco, and alcohol use, which may affect sleep quality and patterns.
• Multivariable analyses indicated associations between coffee use and sleep duration (p = .047), and between alcohol use and M10 onset time (p = .003).
• The relative amplitude of activity was associated with coffee and alcohol use (p = .003 and p = .005, respectively).
• The findings suggest a bidirectional relationship between substance use and sleep/wake cycles in euthymic individuals with bipolar disorder.
• These preliminary results highlight the need for further research to confirm the associations in additional samples.

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