Association between sleep disturbance and metabolic dysfunctions in adipose tissue: Insights into melatonin's role

May 16, 2025Biochemical and biophysical research communications

Link between sleep problems and fat tissue metabolism, with a focus on melatonin’s role

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Abstract

Melatonin imbalance due to sleep disturbances is associated with metabolic dysfunction and increased fat storage.

  • Sleep disturbances are linked to various metabolic disorders, including insulin resistance and obesity.
  • Melatonin regulates processes in adipose tissue such as fat accumulation and energy expenditure.
  • Circadian rhythms synchronize metabolic functions with environmental cues like light and feeding times.
  • Disruption of circadian rhythms may lead to adverse effects on metabolic health through melatonin signaling.
  • Understanding the role of melatonin in adipose tissue could inform the development of new therapies for obesity.

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