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Melatonin: A New-Generation Therapy for Reducing Chronic Pain and Improving Sleep Disorder-Related Pain
Melatonin as a New Treatment for Reducing Chronic Pain and Pain from Sleep Disorders
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Abstract
Melatonin is produced in most living organisms and plays a critical role in regulating circadian rhythms.
- Endogenous melatonin contributes to circadian rhythms in diurnal animals but not in nocturnal animals.
- Circadian rhythms influence the timing and secretion of hormones and neurotransmitters.
- Disturbances in circadian rhythms can lead to abnormal production of hormones and chemicals.
- The human circadian system aligns with physiological functions and metabolism.
- Exogenous melatonin has been reported to have analgesic and neuroprotective effects in chronic pain.
- Chronotherapy utilizing melatonin may be advantageous in treating chronic pain.
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