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How Light, Food, and Drugs Change Body's Natural Rhythms

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

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Abstract

Daily restricted feeding influences clock gene expression in various mouse tissues, excluding the SCN.

  • Daily restricted feeding aligns circadian rhythms in the central nervous system and peripheral tissues.
  • Clock gene expression is affected in the liver, lung, and heart due to feeding patterns.
  • Increased locomotor activity occurs 2-3 hours before feeding, known as food-anticipatory activity (FAA).
  • Peripheral clocks in organs like the liver and heart can be entrained by daily restricted feeding.
  • The exact mechanisms behind FAA and the food-entrainable peripheral oscillator (FEPO) remain unknown.

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