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The adjustment and manipulation of biological rhythms by light, nutrition, and abused drugs
How Light, Food, and Drugs Change Body's Natural Rhythms
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Abstract
Daily restricted feeding influences clock gene expression in various mouse tissues, excluding the SCN.
- Daily restricted feeding aligns circadian rhythms in the central nervous system and peripheral tissues.
- Clock gene expression is affected in the liver, lung, and heart due to feeding patterns.
- Increased locomotor activity occurs 2-3 hours before feeding, known as food-anticipatory activity (FAA).
- Peripheral clocks in organs like the liver and heart can be entrained by daily restricted feeding.
- The exact mechanisms behind FAA and the food-entrainable peripheral oscillator (FEPO) remain unknown.
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