Advanced drug delivery reviews

How Light, Food, and Drugs Change Body's Natural Rhythms

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

Daily restricted feeding influences clock gene expression in various mouse tissues, excluding the SCN.

  • Daily restricted feeding aligns circadian rhythms in the central nervous system and peripheral tissues.
  • Clock gene expression is affected in the liver, lung, and heart due to feeding patterns.
  • Increased locomotor activity occurs 2-3 hours before feeding, known as food-anticipatory activity (FAA).
  • Peripheral clocks in organs like the liver and heart can be entrained by daily restricted feeding.
  • The exact mechanisms behind FAA and the food-entrainable peripheral oscillator (FEPO) remain unknown.

Simplified

Full Text

Full text is available at the source.
View Full Text ↗

Related papers

Nov '09
Body Clocks Outside the Main Brain Timer Influenced by Methamphetamine and Food Restriction
cited by 80 papers
journal article
Jan '10
How damage to the middle hypothalamus affects feeding-related daily activity patterns and liver clock gene expression in mice
cited by 34 papers
research support, non-u.s. gov't
Apr '11
Liver, small intestine, and colon body clocks differ in how they keep time under constant light and adjust to timed feeding
cited by 77 papers
research support, non-u.s. gov't
May '13
Light and feeding influence the internal daily clock in a marine fish (Sparus aurata)
cited by 94 papers
research support, non-u.s. gov't
Apr '11
Brain mechanisms behind daily rhythms of food anticipation
cited by 293 papers
research support, non-u.s. gov't
Aug '10
How feeding schedules affect activity and daily gene patterns in the brain and liver of zebrafish under different light and feeding setups
cited by 81 papers
research support, non-u.s. gov't
Sep '09
Feeding times influence daily movement patterns and internal clock gene activity in zebrafish brain
cited by 46 papers
research support, non-u.s. gov't
Jan '11
Feeding times align daily gene rhythms in the brain and liver of goldfish
cited by 62 papers
research support, non-u.s. gov't
Nov '05
How Daily Body Clocks Affect Anticipatory Behavior and Response to Drug Treatment
english abstract
Aug '11
Daily timed feeding causes regular daily changes in a hormone gene in mouse body fat
top 30% journal
cited by 32 papers
research support, non-u.s. gov't

What Lands in Your Inbox Each Week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • ✅direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free

Recent issues from the circadian biology brief

issue #50
Afternoon workouts beat morning sessions for fat loss — and your genes may explain why
6 days ago7 studies
issue #49
Your body clock controls which drugs work — and a protein called gp78 is why
1 week ago7 studies
issue #48
A blood test can now estimate your internal clock time using just 60 proteins
2 weeks ago7 studies
issue #47
Your body clock controls liver fibrosis — and scientists just found the on/off switch
3 weeks ago7 studies
issue #46
Night shift workers' metabolomes fall out of sync — and glucose pays the price
4 weeks ago7 studies
issue #45
80% of FDA-approved drug targets show clock-dependent activity — timing may be everything
5 weeks ago7 studies
issue #44
Sleeping late on weekends is independently linked to higher cardiovascular disease risk
6 weeks ago7 studies
issue #43
A smartphone app cut mood episode recurrence 3.4x in people with depression and bipolar disorder
7 weeks ago7 studies
issue #42
Morning cancer immunotherapy linked to 49% vs 40% disease control rate in 969 patients
8 weeks ago7 studies
issue #41
Timing cancer treatment before 3pm nearly doubled survival in lung cancer patients
9 weeks ago7 studies
explore the archive
See more issues from the circadian biology brief