Higher prevalence of intentional self-harm in bipolar disorder with evening chronotype: A finding from the APPLE cohort study

Eighteen percent of patients with bipolar disorder reported self-harm, with 37% of those with an evening chronotype engaging in this behavior.

• The evening chronotype group exhibited a higher rate of self-harm compared to intermediate and morning chronotypes.
• Self-harm rates were 37% for evening, 13% for intermediate, and 10% for morning chronotype.
• The odds of self-harming significantly increased from morning to intermediate to evening chronotype, with odds ratios of 1.00, 1.56, and 3.61, respectively.
• The findings indicate a potential link between chronotype and self-harm in individuals with bipolar disorder.
• Limitations include the cross-sectional design and a small sample size.

AI simplified