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Chronotype in bipolar disorder: an 18-month prospective study
Sleep-wake patterns in bipolar disorder over 18 months
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Abstract
Among 80 euthymic patients, 43.8% exhibited moderate morningness.
- is associated with higher rates of obesity or overweight.
- Patients with an evening preference reported greater anxiety.
- Better functioning was linked to evening chronotype.
- Eveningness correlated with more frequent mood episodes but not with psychiatric hospitalizations.
- A tendency toward depressive episodes was observed in patients with evening chronotype.
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Key numbers
4 of 80
Patients with
4 patients were moderately evening type out of 80 total BD patients.
R = 0.34
Increase in anxiety levels
Nonparametric linear regression shows a correlation between MEQ scores and anxiety levels.
p = 0.04
Mood episodes associated with eveningness
Logistic regression analysis indicates a significant relationship between eveningness and mood episodes.