BMC infectious diseases

Higher blood clotting markers and platelet activity linked to long-term COVID-19 symptoms

Updated

Abstract

Essence

People who developed long COVID showed early and persistent blood signatures of immunothrombosis, platelet activation, and vascular dysfunction after SARS-CoV-2 infection.

Evidence

A longitudinal multi-omics study of 75 COVID-19 patients combined multiplex plasma assays, LC-MS proteomics, and whole-blood flow cytometry to compare those with and without .

Caveat

This was a small association study, so the candidate biomarkers are not yet validated as predictive tests for PASC.

Simplified

Key numbers

1.3×
Elevated Plasma Factor-IX Levels
Factor-IX levels in patients with compared to those without.
75
Total Participants
Total number of participants diagnosed with COVID-19 in the study.
1.3%
Mortality Rate
Mortality rate across all disease severity groups in the study.

Full Text

We can’t show the full text here under this license.

what lands in your inbox each week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free