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The Role of BMAL1 in Regulating Circadian Rhythms During Airway Remodeling in Asthma
BMAL1’s role in controlling daily body clocks during airway changes in asthma
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Abstract
BMAL1, a core circadian clock gene, significantly influences the proliferation and differentiation of airway stem cells.
- Asthma is characterized by airway inflammation, hyperresponsiveness, and remodeling.
- The circadian clock regulates key processes that are essential for normal respiratory function.
- The relationship between circadian clock genes and asthma airway remodeling remains unclear.
- Recent advances in asthma research highlight the importance of airway remodeling in disease progression.
- Unresolved questions exist regarding the function of the BMAL1 gene in asthma pathogenesis.
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