Immediate body and mind effects of different oral and under-the-tongue psilocybin and psilocin treatments in a controlled trial

Psilocybin, a compound derived from hallucinogenic mushrooms, has shown therapeutic potential for neuropsychiatric conditions.

• Psilocybin is metabolized into psilocin, which is responsible for its psychoactive effects.
• Recent trials have focused on orally administered synthetic psilocybin.
• Alternative formulations and delivery methods for psilocybin may provide therapeutic benefits.
• The effects of these alternative approaches are not well understood.

Simplified