Quality of bowel preparation for colonoscopy in patients on glucagon-like peptide-1 receptor agonists

🥉 Top 5% JournalNov 18, 2024Gastrointestinal endoscopy

Bowel cleaning quality during colonoscopy in patients taking GLP-1 diabetes medications

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Abstract

Among 6235 patients, those using glucagon-like peptide-1 receptor agonists (GLP-1 RAs) had significantly poorer bowel preparation quality during colonoscopy.

  • Patients on GLP-1 RAs were significantly more likely to have inadequate bowel preparation compared to those not using these medications.
  • Higher total Boston Bowel Preparation Scale scores were observed in control patients, indicating better preparation quality.
  • Factors associated with suboptimal bowel preparation included being an inpatient, male sex, higher body mass index, type 2 diabetes, inflammatory bowel disease, opioid use, heart failure, and cirrhosis.
  • No significant differences were found between different classes of GLP-1 RAs regarding bowel preparation quality.

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