Bowel cleaning quality in patients using diabetes drugs called GLP-1 agonists: a review and combined analysis

Mean bowel preparation quality score was significantly lower by 0.36 in patients using GLP-1 receptor agonists compared to controls.

• No significant difference was found in the rate of inadequate bowel preparation events between those using GLP-1 receptor agonists and the control group.
• The odds ratio for inadequate preparation events was 1.00, indicating no increased risk associated with GLP-1 RA use.
• The mean Boston Bowel Preparation Scale score in the GLP-1 RA group was negatively impacted, suggesting poorer bowel preparation quality.
• The findings indicate that GLP-1 RA use may not affect overall bowel preparation for colonoscopy.
• Discontinuation of GLP-1 RAs prior to colonoscopy is not recommended based on the current evidence.

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