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Effect of Glucagon-Like Peptide-1 Receptor Agonists on Bowel Preparation for Colonoscopy: A Systematic Review and Meta-Analysis
Glucagon-like peptide-1 drugs may affect bowel cleaning for colonoscopy: A review and combined analysis
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Abstract
The inadequate bowel preparation rate was 2.10 times higher in patients using glucagon-like peptide-1 receptor agonists compared to controls.
- GLP-1 receptor agonists are associated with a higher rate of inadequate bowel preparation during colonoscopy.
- The odds ratio for inadequate bowel preparation in GLP-1RA users is 2.10, indicating a significant increase in risk.
- Mean Boston Bowel Preparation Scale scores are lower in the GLP-1RA group compared to the control group.
- The mean difference in Boston Bowel Preparation Scale score is -0.34, suggesting poorer bowel preparation quality with GLP-1RAs.
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