Circadian clock in thyroid cancer: Effects and mechanisms

Nov 17, 2025Chronobiology international

The circadian clock may affect thyroid cancer and its processes.

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Abstract

Circadian rhythm disruption is associated with an increased risk of thyroid cancer.

  • The circadian clock regulates key physiological processes that are crucial for thyroid function.
  • Shift work and exposure to artificial light at night may disrupt circadian rhythms.
  • Disruption of these rhythms could contribute to thyroid carcinogenesis through various biological mechanisms.
  • Molecular pathways connecting clock dysregulation to cancer include oncogenic signaling and immune evasion.
  • Chronotherapy may serve as a potential precision oncology strategy targeting these disruptions.

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