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Circadian Clocks and Cancer: Timekeeping Governs Cellular Metabolism
Body’s Internal Clocks and Cancer: How Daily Timing Controls Cell Metabolism
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Abstract
Disruption of the circadian clock is associated with altered timekeeping and detrimental effects, including cancer.
- The circadian clock influences various physiological processes across virtually all cells.
- Genetic disruption of the clock may affect multiple networks involved in tumor initiation and progression.
- Circadian control is linked to cellular metabolism in both tumors and the wider organism.
- Recent advances have highlighted the metabolic changes in transformed cells and the heterogeneity of tumors.
- There are ongoing discussions about the implications of circadian control on metabolic pathways related to cancer.
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