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Body Clock Rhythms in the Immune System
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Abstract
Most immune cells express circadian clock genes that are involved in a wide array of daily physiological processes.
- Circadian rhythms influence immune cell functions, including cytokine synthesis and release.
- Daily variations occur in immune responses, such as cell migration to sites of infection.
- Alterations in circadian rhythms may lead to disrupted immune responses, evidenced by clock gene mutations in mice.
- Environmental disruptions, like shift work, can negatively affect the immune system.
- Impacts on human health related to circadian regulation of immune functions require further research.
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