Circadian Clocks Make Metabolism Run

Disruption of the circadian system in rodents is associated with various metabolic disturbance phenotypes.

• The circadian system plays a crucial role in regulating nearly all physiological and behavioral processes in mammals.
• Peripheral clocks in metabolic organs are involved in maintaining glucose, lipid, and protein balance at both organismal and cellular levels.
• Studies indicate that disturbances in the circadian clock may contribute to the onset of metabolic diseases in humans.
• Recent findings suggest that the circadian system coordinates metabolism in alignment with the body's daily rhythms.

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