Circadian Disruption in Night Shift Work and Its Association with Chronic Pulmonary Diseases

Feb 16, 2023Advanced biology

Night Shift Work Disrupts Body Clock and Is Linked to Long-Term Lung Diseases

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Abstract

Night shift work (NSW) is associated with disruptions in circadian rhythms that may impact lung inflammation.

  • NSW causes misalignment between internal biological clocks and external environmental signals.
  • Circadian disruption may influence inflammatory and metabolic processes in the body.
  • Clock genes have been identified in the lung, suggesting mechanisms for circadian misalignment in respiratory diseases.
  • Lung inflammation is linked to chronic conditions such as asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and COVID-19.
  • Current understanding of circadian disruption's effects on lung health is limited, indicating a need for further research.

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