Disrupted body clock genes in long-term lung diseases

Circadian clock disruption is associated with multiple detrimental effects in chronic lung diseases.

• Disrupted circadian rhythms may lead to increased oxidative stress in lung tissues.
• Alterations in inflammatory responses could result from circadian clock disruptions.
• Metabolic imbalances are potentially linked to changes in the circadian clock.
• Dysregulated mucus secretion may occur due to disturbances in circadian rhythms.
• Changes in autophagy processes could be influenced by circadian clock alterations.
• Pulmonary function is likely affected by the disruption of the circadian molecular clock.

Simplified