Trends in pharmacological sciences

Treatments targeting the body’s internal clock for long-term lung diseases

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

The circadian clock is a key factor in the pathobiology of chronic pulmonary diseases.

  • Disruption of the circadian clock in the lungs is associated with chronic pulmonary diseases.
  • Pharmacological manipulation of the circadian clock may offer new therapeutic strategies.
  • No current efforts have integrated recent findings for treating chronic lung diseases.
  • Potential candidate clock genes exist that could be targeted for therapy.
  • A roadmap is proposed to advance the development of circadian clock-based treatments.

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Competing interests

Declaration of interests The authors have declared that no conflict of interest exists.
PubMed

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