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Abstract
Circadian rhythms play a critical role in regulating immune responses and metabolism in cancer.
- Altered sleep-wake cycles may disrupt host metabolism and immune function.
- Dysregulation of circadian-related genes is associated with various cancers.
- Small metabolites from metabolic pathways are often disrupted in cancerous conditions.
- Circadian genes influence both metabolism and the availability of metabolites in the tumor microenvironment.
- Changes in metabolite levels can affect the movement of immune cells to tumor sites.
- A compromised immune response in tumors may promote cancer cell growth and spread.
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