Critical reviews in oncology/hematology

The important link between the body’s daily rhythm and cancer

Updated

Abstract

Disruption of circadian rhythms is associated with increased risks of various diseases, including cancers.

  • Circadian rhythms regulate physiological processes such as metabolism, hormone secretion, and sleep.
  • Epidemiological and clinical data suggest a connection between circadian rhythm disruption and cancer.
  • Oncogenic processes may interfere with the body's natural circadian balance.
  • Integrating circadian biology into cancer research could enhance the effectiveness of cancer treatments.
  • Pharmacological modulation of core clock genes represents a potential new strategy in cancer therapy.

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Competing interests

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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