Rhythm is essential: Unraveling the relation between the circadian clock and cancer

Jan 26, 2025Critical reviews in oncology/hematology

The important link between the body’s daily rhythm and cancer

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Abstract

Disruption of circadian rhythms is associated with increased risks of various diseases, including cancers.

  • Circadian rhythms regulate physiological processes such as metabolism, hormone secretion, and sleep.
  • Epidemiological and clinical data suggest a connection between circadian rhythm disruption and cancer.
  • Oncogenic processes may interfere with the body's natural circadian balance.
  • Integrating circadian biology into cancer research could enhance the effectiveness of cancer treatments.
  • Pharmacological modulation of core clock genes represents a potential new strategy in cancer therapy.

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