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Circadian misalignment increases 24‐hour acylated ghrelin in chronic shift workers: a randomized crossover trial
Body clock mismatch raises 24-hour hunger hormone levels in long-term shift workers
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Abstract
Circadian misalignment led to a 17% increase in 24-hour acylated ghrelin levels in chronic shift workers.
- Chronic night shift workers experienced a 14% increase in reported hunger at breakfast during circadian misalignment.
- No significant changes were observed in fasting or post-meal energy expenditure despite the misalignment.
- Behavioral activity levels were approximately 38% higher during circadian misalignment, along with increased sleepiness.
- The findings suggest that circadian misalignment may disrupt energy balance regulation in chronic shift workers.
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