Biological reviews of the Cambridge Philosophical Society

Daily rhythms of the body and gut bacteria during infection

Updated

Abstract

Circadian rhythms regulate various biological processes and interact with gut microbiota in response to pathogens.

  • Circadian rhythms influence metabolism, immune responses, and microbial exposure in organisms.
  • There is a bidirectional interaction between host circadian clocks and gut microbiota.
  • Host circadian clocks may enhance the immune system's ability to combat pathogen infections.
  • Circadian clocks have direct effects on viral activity, including the entry and replication of SARS-CoV-2.
  • Strategies to realign circadian rhythms, such as chronotherapy and dietary changes, could support host health.

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