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Integration of circadian rhythms and immunotherapy for enhanced precision in brain cancer treatment
Using body clock timing to improve immune therapy for brain cancer
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Abstract
Circadian rhythms are linked to neurodegenerative diseases and increased cancer vulnerability.
- Disruptions in circadian rhythms may influence physiological processes related to cancer and neurodegeneration.
- Immunotherapy has shown limited efficacy in treating brain malignancies.
- Circadian regulation affects immune responses, including how immune cells are localized and function.
- Dysregulation of circadian rhythms could impair anti-cancer immunity.
- Current immunotherapeutic approaches for brain cancer include immune checkpoint blockades and adoptive cellular therapies.
- Future strategies may involve chronotherapy and personalized treatment schedules to enhance immunotherapy effectiveness.
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