Circadian rhythms in haematological malignancies: therapeutic potential and personalised interventions

Nov 20, 2024EBioMedicine

Body Clock Patterns in Blood Cancers: Treatment Possibilities and Personalized Care

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Abstract

Disruptions in the circadian clock may be involved in cancer progression.

  • The circadian clock regulates the rhythmic expression of many genes and biological processes.
  • Genetic and environmental disruptions to the circadian system are associated with cancer progression.
  • Clock genes may serve as diagnostic and prognostic biomarkers for haematological malignancies.
  • Optimising treatment timing through circadian rhythms could enhance treatment efficacy.
  • Strategies for personalised chronobiological interventions are discussed, particularly for cutaneous lymphoma.

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