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How Body Clocks Relate to Mood Disorders and the Role of Light
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Abstract
Mood disorders are strongly associated with abnormal sleep and circadian rhythms.
- Disruptions to light/dark cycles and sleep/wake patterns may precipitate episodes of mood disorders.
- Specific circadian phenotypes are linked to various mood disorders, including seasonal affective disorder, major depressive disorder, and bipolar disorder.
- Neuronal mechanisms connect the circadian clock with mood regulation.
- Therapies targeting the circadian system have shown therapeutic potential in some cases.
- Current knowledge could aid in developing individually designed treatments for mood disorders.
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