Circadian rhythms and obesity: Timekeeping governs lipid metabolism

Jul 14, 2020Journal of pineal research

Body Clock Controls Fat Metabolism and Its Link to Obesity

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Abstract

Circadian clocks produce oscillations with a period of approximately 24 hours.

  • Circadian clocks drive rhythms in physiology to synchronize bodily functions with the external environment.
  • Disruption of circadian rhythms can have long-term effects on metabolic health.
  • There is an increasing recognition of the interaction between circadian rhythms and lipid metabolism in relation to obesity.
  • Factors such as hormones, the gut microbiome, and energy metabolism may link the circadian clock to lipid metabolism.
  • Deregulation of circadian clock-lipid metabolism interactions could heighten the risk of obesity and further disrupt circadian organization.
  • Feeding time and dietary nutrients are key environmental factors that influence the relationship between circadian rhythms and lipid metabolism.

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