Body Clock Controls Fat Metabolism and Its Link to Obesity

Circadian clocks produce oscillations with a period of approximately 24 hours.

• Circadian clocks drive rhythms in physiology to synchronize bodily functions with the external environment.
• Disruption of circadian rhythms can have long-term effects on metabolic health.
• There is an increasing recognition of the interaction between circadian rhythms and lipid metabolism in relation to obesity.
• Factors such as hormones, the gut microbiome, and energy metabolism may link the circadian clock to lipid metabolism.
• Deregulation of circadian clock-lipid metabolism interactions could heighten the risk of obesity and further disrupt circadian organization.
• Feeding time and dietary nutrients are key environmental factors that influence the relationship between circadian rhythms and lipid metabolism.

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