World journal of gastroenterology

Body Clock Patterns and Their Role in Digestive Diseases

Updated

Abstract

Circadian rhythm disruptions are associated with the development of digestive pathologies, including irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD).

  • Circadian rhythms play a crucial role in digestive health, influencing mechanisms that affect organ function.
  • Disturbed circadian rhythms can lead to a loss of synchronicity between the central and peripheral biological clocks.
  • This lack of coordination may alter tissue function and potentially cause long-term damage to digestive organs.
  • Life habits such as sleep, exercise, social interactions, and meal timing are important for maintaining stable circadian rhythms.
  • Alterations in circadian rhythms are linked to changes in gut motility and microbiota composition.
  • Promoting life habits that align with circadian rhythms could help prevent digestive diseases.

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Funding

Competing interests

Conflict-of-interest statement: The authors have no conflict of interest to declare.
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