Effects of dietary consumption of cranberry powder on metabolic parameters in growing rats fed high fructose diets

The medium level of cranberry powder (CP) in the diet produced a better response in metabolic parameters than lower or higher levels.

• Fasting plasma glucose and triglycerides were higher with a high fructose diet and reduced by cranberry powder.
• The area under the curve for an oral glucose tolerance test was 35-50% higher in high fructose diet rats compared to controls but normalized with low or medium CP diets.
• Fasting plasma insulin tended to be lower in rats fed cranberry powder.
• Homeostatic models of insulin resistance and β-cell function were lowest in rats fed low or medium CP diets.
• Kidney weight increased in high fructose diet rats but decreased to normal levels with cranberry powder.
• Overall, inclusion of cranberry powder modulated some metabolic parameters associated with metabolic syndrome.

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