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Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals
Daily gene activity patterns in multiple tissues responding to limited-time feeding in mammals
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Abstract
Nearly 80% of all genes exhibit differential expression or rhythmicity in at least one tissue during time-restricted feeding (TRF).
- TRF significantly alters gene expression across multiple organs and brain regions.
- Gene expression changes occur in a tissue- and pathway-specific manner.
- The study identifies a potential molecular basis for the health benefits associated with TRF.
- Findings provide a foundation for future studies on time-restricted eating (TRE) interventions in humans.
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