Time-restricted feeding regulates molecular mechanisms with involvement of circadian rhythm to prevent metabolic diseases

Apr 30, 2021Nutrition (Burbank, Los Angeles County, Calif.)

Time-limited eating may help prevent metabolic diseases by influencing body clock-related molecular processes

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Abstract

Time-restricted feeding (TRF) may improve metabolic health by regulating circadian rhythms.

  • Lifestyle and genetic changes in circadian rhythm can increase the risk and severity of metabolic diseases.
  • TRF regulates when food is consumed, which helps protect against metabolic disorders linked to poor nutrient intake.
  • The coordination of the circadian clock and nutrient-sensing pathways is important for maintaining metabolic health.
  • TRF can enhance nutrient utilization based on food availability and support cellular balance.
  • Adjusting daily eating and fasting periods may recalibrate the circadian clock, reducing negative effects of nutrient imbalance.
  • TRF has the potential to restore metabolic rhythms and improve gene expression related to metabolism.

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