Brain clock networks control daily temperature preferences in fruit flies

Dorsal neurons 2 (DN2s) are identified as the main clock for temperature preference rhythm (TPR) in Drosophila.

• Body temperature rhythm (BTR) in animals, including Drosophila, is influenced by daily temperature preference rhythm (TPR).
• Dorsal neurons 2 (DN2s) and posterior DN1s (DN1ps) show increased contact during the day, suggesting a dynamic relationship.
• Silencing either DN2s or DN1ps results in a lower temperature preference, indicating their roles in regulating TPR.
• Temporal control of the microcircuit between DN2s and DN1ps may contribute to the regulation of TPR.
• Anterior DN1s (DN1as) are also identified as significant for TPR, highlighting the complexity of the clock networks involved.

Simplified