Circadian Rhythm of Temperature Preference and Its Neural Control in Drosophila

Drosophila exhibit a daily circadian clock-dependent temperature preference rhythm (TPR) that resembles mammalian body temperature rhythm (BTR).

• Ectotherms like Drosophila regulate body temperature behaviorally rather than through internal energy.
• The dorsal neuron 2 s (DN2s) is identified as sufficient for TPR, independent of pacemaker neurons involved in locomotor activity.
• The control of TPR in Drosophila may share mechanisms with the regulation of BTR in mammals.
• This study introduces a novel DN2-based neural circuit that specifically regulates TPR.

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