Recent Discoveries About the Biological Effects of Fluorine-Containing Pyridine and Its Related Compounds

Fluorine-containing pyridine derivatives are integrated into numerous FDA-approved drugs.

• These compounds enhance drug potency, selectivity, metabolic stability, and pharmacokinetics.
• Recent advances highlight their pharmacological applications in anticancer, antidiabetic, antioxidant, and anti-Alzheimer's activities.
• The review compiles insights on the structure-activity relationship and mechanisms of action for these derivatives.
• The findings may inspire new directions in drug discovery.

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